Pixar feature-length animation films have been pulling at our heart strings, playing them like a finely-tuned violin for 18 years now. The computer-animation studio has produced some of the greatest animated films, or just films in general, in the last two decades and longer. What makes Pixar that phenomenal at story telling (26 Academy Awards in thirteen movies, your welcome) is the studios ability to understand what it is to be human, what makes us tick–understanding and showing to us that they know exactly what makes us laugh and cry. Be it through toys, bugs, cars, or monsters, every time we finish a Pixar movie we feel a bit more humble in our nature as we appreciate the great things we have in life. And Pixar knows exactly how to take an arrow and shot it straight at our pouting emotions to give us some the saddest, yet most human moments in cinema.
Chris Combs
XtremeGoof Kingdom 
I’d have had Toy Story inferno as number 1, I was extremely distressed. Have you seen the Toy Story 3 prank ending? —> http://www.youtube.com/watch?v=phFISjORzQs
Other than the ‘I don’t have a dad’ scenes in Up you’ve pretty much nailed it. Would’ve been a lot harder to narrow it down to 10 though if it was all Disney films! Obviously Muphasa dying would be #1 in that list.
The ‘I don’t have a dad’ moment in UP slipped my mind. That would have definitely been on this list. Good call.